Anti-FXYD6 Rabbit Polyclonal Antibody (Cy3®)
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Product Details & Documents
The mammalian FXYD family maintains Na+ and K+ gradients between the intracellular and extracellular milieus of cells in processes such as renal Na+-reabsorption, muscle contraction and neuronal excitability. FXYDs are single-span membrane proteins that share a 35 amino acid signature domain, beginning with the sequence PFXYD and containing seven invariant and six conserved amino acids. Members of the FXYD family include FXYD1 (PLM, phospholemman), FXYD2 (the g subunit of the Na+/K+-ATPase), FXYD3 (Mat8, mammary tumor protein), FXYD4 (CHIF) and FXYD5 (RIC). FXYD6 is expressed in various epithelial cells bordering the endolymph space and in the auditory neurons. FXYD6 co-localizes with Na+/K+-ATPase in the stria vascularis and can be co-immunoprecipitated with Na+/K+-ATPase. After expression, FXYD6 associates with Na+/K+-ATPase alpha1-beta1 and alpha1-beta2 isozymes, which are preferentially expressed in different regions of the inner ear and also with gastric and non-gastric H+/K+-ATPase.
Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200
Type: Primary
Antigen: FXYD6
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Documents
bs-13234R-CY3
Datasheet
Specifications
- Size:100 µL
- Cross Adsorption:No
- Clonality:Polyclonal
- Purification:Purified by Protein A
- Form:liquid
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Isotype:IgG
- Host:Rabbit
- Concentration:1 μg/μl
- Cat. No.:10292-258
- Flow Cytometry:Yes
- Reactivity:Human|Rat|Mouse
- Shipping Temperature:4°C
- Antibody Type:Primary
- Antigen Symbol:FXYD6
- Gene ID:53826
- ImmunoChemistry:Yes
- Conjugation:Cy3®
- Antigen Synonyms:FXYD domain containing ion transport regulator 6|UNQ521/PRO1056|FXYD6_HUMAN.|Phosphohippolin|FXYD domain containing ion transport regulator 6 precursor
- Antigen Name:FXYD Domain Containing ion transport Regulator 6
- Storage Temperature:Store at 4°C for 12 months
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