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Specifications
- Antibody Type:Primary
- Antigen Name:Platelet-derived Growth Factor Alpha And Beta
- Antigen Symbol:PDGFA + PDGFB
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Size:100 µL
- Cross Adsorption:No
- Form:liquid
- Antigen Synonyms:Proto-oncogene c-Sis |Becaplermin |FLJ12858 |v sis platelet derived growth factor beta polypeptide simian sarcoma viral oncogene homolog|PDGF A |Platelet derived growth factor beta polypeptide simian sarcoma viral v-sis oncogene homolog |PDGF-2 |PDGF B |Platelet derived growth factor beta polypeptide |Pdgfb |Platelet-derived growth factor beta polypeptide |Platelet-derived growth factor B chain |SSV |PDGF A chain |PDGF B chain |SIS |PDGF subunit B |PDGFB_HUMAN |Platelet derived growth factor A chain precursor |Platelet derived growth factor alpha polypeptide |Platelet-derived growth factor|PDGF 2 |Platelet-derived growth factor subunit B |beta polypeptide oncogene SIS |PDGF 1 |Platelet derived growth factor B chain precursor |c-sis |platelet-derived growth factor 2 |c sis
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage Temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Purification:Purified by Protein A
- Cat. No.:10274-786
- Supplier no.:BS-12157R-FITC
Specifications
About this item
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: PDGFA + PDGFB
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat