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- Antibody Type:Primary
- Antigen Name:Retinoic Acid Induced 3
- Antigen Symbol:RAI3
- Clonality:Polyclonal
- Conjugation:Cy5®
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human
- Size:100 µL
- Environmentally Preferable:
- Cross Adsorption:No
- Form:liquid
- Antigen Synonyms:Raig 1|GPCR5A|GPCR 5A|RAIG-1|Retinoic acid induced gene 1 protein|G-protein coupled receptor family C group 5 member A|Gprc5a|Retinoic acid-induced gene 1 protein|Orphan G-protein-coupling receptor PEIG-1|RAI 3|Orphan G protein coupling receptor PEIG 1|Retinoic acid responsive|Retinoic acid-induced protein 3.|Retinoic acid responsive gene|RAI3_HUMAN|Orphan G protein coupling receptor PEIG1|Retinoic acid induced 3|Gprc 5a|Raig1|Retinoic acid induced protein 3
- Storage Buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage Temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping Temperature:4°C
- Purification:Purified by Protein A
- Cat. No.:10262-632
- Supplier no.:BS-11580R-CY5
RAI3 is an transmembrane G-protein-coupled receptor that affects many essential biological processes including embryogenesis, cell growth, differentiation, and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, and selective suppression of signals from RAI3 may have a place in breast cancer treatments.
Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200
Type: Primary
Antigen: RAI3
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human