Specifications
- Antibody Type:Primary
- Antigen Name:Tumor Necrosis Factor Receptor Superfamily Member 17
- Antigen Symbol:TNFRSF17
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Reactivity:Human
- Western Blot:Yes
- Size:100 µg
- Epitope:C-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:608
- Antigen Synonyms:TNFRSF13A|CD269|BCMA|BCM
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-BCMA antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide mapping at the C-terminus of human BCMA.
- Purification:Anti-BCMA Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with BCMA from other sources has not been determined.
- Cat. No.:10800-312
- Supplier no.:600-401-Z51
Specifications
About this item
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA (for B cell maturation protein), TACI, and BAFF-R, for BAFF were recently identified. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Recommended Dilutions: ELISA: 1:50,000; Immunohistochemsitry: 10 µg/mL; Immunofluorescence Microscopy: 20 µg/mL; Western Blot: 5 µg/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: TNFRSF17
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity: Human