- Antibody Type:Primary
- Antigen Name:B-cell receptor-associated protein 31
- Antigen Symbol:BCAP31
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µg
- Epitope:Center
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:10134
- Antigen Synonyms:DDCH|DXS1357E|BAP31|CDM|6C6-AG
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-BAP31 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the internal region of human BAP31.
- Purification:Anti-BAP31 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with BAP31 from other sources has not been determined.
- Cat. No.:10802-010
- Supplier no.:600-401-Z33
Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. Bap31 may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopically, is also a potent inducer cell death.
- Recommended Dilutions: ELISA: 1:5000-1:20,000; Immunohistochemsitry: 10 µg/mL; Western Blot: 0.5 - 2 μg/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: BCAP31
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Center
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat