Specifications
- Antibody Type:Primary
- Antigen Name:Serine/Threonine Kinase 17A
- Antigen Symbol:STK17A
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Reactivity:Human
- Western Blot:Yes
- Size:100 µg
- Epitope:N-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:9263
- Antigen Synonyms:DRAK1|DAP kinase-related apoptosis-inducing protein kinase 1
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-DRAK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminus of human DRAK1.
- Purification:Anti-DRAK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. No cross responses to DRAK2, DAP or ZIP kinases.
- Cat. No.:10802-548
- Supplier no.:600-401-AX7
Specifications
About this item
Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
Recommended Dilutions: ELISA: 1:10,000; Immunofluorescence Microscopy: 10 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: STK17A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human