Specifications
- Antibody Type:Primary
- Antigen Name:Telomerase-associated Protein 1
- Antigen Symbol:TEP1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Reactivity:Human
- Western Blot:Yes
- Size:100 µg
- Epitope:C-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:7011
- Antigen Synonyms:TLP1|VAULT2|TP1|Telomerase protein 1|Telomerase-associated protein 1|TROVE1|p240|Telomerase protein component 1
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-DOK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the C-terminus of human DOK1.
- Purification:Anti-DOK1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with DOK1 from other sources has not been determined.
- Cat. No.:10802-454
- Supplier no.:600-401-AW9
Specifications
About this item
Signals from most growth factors and cytokines are transduced by receptor tyrosine kinases or non-receptor tyrosine kinases. Activated tyrosine kinases phosphorylate their substrates, which mediate the cellular response to extracellular stimuli. A long-sought major substrate termed p62dok (downstream of tyrosine kinase) for many tyrosine kinases including c-kit, v-abl, v-Fps, v-Src, v-Fms, and activated EGF, PDGF, IGF, VEGF and insulin receptors was identified recently from human and mouse by several laboratories. Upon phosphorylation, p62dok forms a complex with the ras GTPase-activating protein (RasGAP). p62dok represents a new family with very recently identified p56dok.
Recommended Dilutions: ELISA: 1:10,000; Immunofluorescence Microscopy: 10 ?g/mL; Western Blot: 1 ?g/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: TEP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: C-Terminal
Host: Rabbit
Isotype:
Reactivity: Human