Specifications
- Antibody Type:Primary
- Antigen Name:B-cell lymphoma 2
- Antigen Symbol:BCL2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:100 µg
- Epitope:N-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:596
- Antigen Synonyms:PPP1R50|Bcl-2
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-Bcl-2 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 15 amino acids near the N terminus of human Bcl-2.
- Purification:Anti-Bcl-2 Antibody is purified by ion exchange chromatography. Cross reactivity with Bcl-2 from other sources has not been determined.
- Cat. No.:10800-300
- Supplier no.:200-401-Z43
Specifications
About this item
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis. It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad. Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Recommended Dilutions: ELISA: 1:10,000-1:40,000; Immunohistochemsitry: 2 µg/mL; Immunofluorescence Microscopy: 10 µg/mL; Western Blot: 1 - 4 µg/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: BCL2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse