Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3]
Catalog # 10765-158
Supplier: Prosci
Specifications
- Antibody Type:Primary
- Antigen Name:CD40 molecule, TNF receptor superfamily member 5
- Antigen Symbol:CD40
- Clonality:Monoclonal
- Clone:5C3
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Size:0.5 mg
- Cross Adsorption:No
- Format:purified antibody
- Form:liquid
- Gene ID:P25942
- Antigen Synonyms:CD40
- Storage Buffer:Phosphate-buffered aqueous solution, ph7.2.
- Storage Temperature:The product should be stored undiluted at 4 °C . Do not freeze.
- Shipping Temperature:4 °C
- Tested Applications:Functional
- Purification:The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
- Cat. No.:10765-158
- Supplier no.:76-020
Specifications
About this item
The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.
Type: Primary
Antigen: CD40
Clonality: Monoclonal
Clone: 5C3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: Mouse IgG1, kappa
Reactivity: Human