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Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3]
Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3]
Catalog # 10765-158
Supplier:  Prosci
Anti-CD40 Mouse Monoclonal Antibody [clone: 5C3]
Catalog # 10765-158
Supplier:  Prosci
Supplier Number:  76-020

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    CD40 molecule, TNF receptor superfamily member 5
  • Antigen Symbol:
    CD40
  • Clonality:
    Monoclonal
  • Clone:
    5C3
  • Conjugation:
    Unconjugated
  • Flow Cytometry:
    Yes
  • Host:
    Mouse
  • Isotype:
    IgG1 kappa
  • Reactivity:
    Human
  • Size:
    0.5 mg
  • Cross Adsorption:
    No
  • Format:
    purified antibody
  • Form:
    liquid
  • Gene ID:
    P25942
  • Antigen Synonyms:
    CD40
  • Storage Buffer:
    Phosphate-buffered aqueous solution, ph7.2.
  • Storage Temperature:
    The product should be stored undiluted at 4 °C . Do not freeze.
  • Shipping Temperature:
    4 °C
  • Tested Applications:
    Functional
  • Purification:
    The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
  • Cat. No.:
    10765-158
  • Supplier no.:
    76-020

Specifications

About this item

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Type: Primary
Antigen: CD40
Clonality: Monoclonal
Clone: 5C3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: Mouse IgG1, kappa
Reactivity: Human