Specifications
- Antibody Type:Primary
- Antigen Name:nuclear receptor subfamily 1, group H, member 2
- Antigen Symbol:NR1H2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:0.02 mg
- Epitope:near the N-Terminus
- Cross Adsorption:No
- Form:Liquid
- Gene ID:P55055
- Antigen Synonyms:NR1H2
- Storage Buffer:LXR-B Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage Temperature:LXR-B antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:LXR-B antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus human LXR-B. The immunogen is located within the first 50 amino acids of LXR-B.
- Purification:LXR-B Antibody is affinity chromatography purified via peptide column.
- Cat. No.:10750-794
- Supplier no.:5579_S
Specifications
About this item
LXR-B Antibody: LXR-B belongs to the Liver X Receptor family that encodes highly homologous transcription factors. Like the highly homologous LXR-A, LXR-B forms heterodimers with the retinoic acid receptor RXRalpha, which function as sensors for cellular oxysterols which when activated, increase the expression of genes that control sterol and fatty acid metabolism and homeostasis. Recent experiments have indicated that the LXRs can also modulate both innate and adaptive immune responses. Other studies suggest that genetic variability at the LXR-B gene locus may be a risk factor for Alzheimer's disease. One hypothesis postulates that LXR may be upstream of ApoE and potentiates the risk associated effects of the epsilon3 allele.
Type: Primary
Antigen: NR1H2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat