- Antibody Type:Primary
- Antigen Name:2'-5'-oligoadenylate synthetase-like
- Antigen Symbol:OASL
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:0.02 mg
- Epitope:near the N-Terminus
- Cross Adsorption:No
- Form:Liquid
- Gene ID:Q15646
- Antigen Synonyms:OASL
- Storage Buffer:OASL Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular Weight:Predicted: 57 kDa Observed: 65 kDa
- Storage Temperature:OASL antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:OASL antibody was raised against a 17 amino acid peptide near the amino terminus of human OASL. The immunogen is located within the first 50 amino acids of OASL.
- Tested Applications:Immunocytochemistry
- Purification:OASL antibody is affinity chromatography purified via peptide column.
- Cat. No.:10748-910
- Supplier no.:7775_S
OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains. It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor.
Type: Primary
Antigen: OASL
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat