Human Recombinant St21 (from HEK293 Cells)
10797-504
: Prosci
:
- Protein/Peptide Type:Recombinant
- Source:HEK293 cells
- Species:Human
- Size:0.2 mg
- Tag sequence:C-Fc Tag
- Biological Activity:Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL33 at 10μg/ml (100μl/well) can bind rh IL1RL1 /ST2 Fc Chimera with a linear range of 0. 3-5μg/ml.
- Protein Synonyms:ST2|ST2V|DER4|ST2L|T1|IL33R|FIT-1|IL1RL1
- Protein/Peptide Name:St21
- Purity:>95% as determined by SDS-PAGE.
- Molecular Weight:61.6 kDa
- Formulation:Lyophilized, 50 mM tris, 100 mM glycine, pH7.5
- Tested Applications:Western Blot
- Cat. No.:10797-504
- Supplier no.:96-428
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.