Human Recombinant TNFR-1 (from E. coli)

Tumor necrosis factor receptor type 1 (TNFR-1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNF-α). TNFR-1 activates NF-κB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication.

High quality
Low endotoxin
Affordable

: For research use only.

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Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/Peptide Type:
Recombinant
Source:
E. coli
Species:
Human
Storage Conditions:
–20 °C
Endotoxin Content:
Endotoxin LAL (EU/µg) ≤1
Biological Activity:
Bioactivity Assay: Neutralization of human TNF alpha induced L929 cell cytolysis, ED₅₀ ≤100 ng/ml, Bioactivity ≥1.0×10⁴ units/mg
Gene ID:
P19438
Reconstitution Instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-Free:
Y
Protease-free:
N
Animal-Free:
N
Protein Synonyms:
TNFRSF1A|TNFR55|CD120a|TNFAR
Protein/Peptide Name:
TNFR-1
Purity:
≥95%
Molecular Weight:
18.3 kDa
Sequence:
MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM GQVEISSCTV DRDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQI EN
Endotoxin Level:
Low
Formulation:
10 mM Sodium phosphate, pH 7.5
Nuclease-free:
N
Grade:
RUO
Shipping Temperature:
RT
Tested Applications:
Bioassay

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