About this item
Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. M-CSF also acts through the colony stimulating factor 1 receptor (CSF1R) to modulate processes involved in immunology, bone metabolism, fertility, and pregnancy. Human M-CSF shows activity on mouse cells; however, mouse M-CSF shows no activity on human cells.
- High quality
- Low endotoxin
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Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Mouse
- Storage Conditions:–20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity Assay: NFS-60 cell proliferation, ED₅₀ ≤10 ng/ml, Bioactivity ≥1.0×10⁵ units/mg
- Gene ID:P07141
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:N
- Protein Synonyms:CSF-1|mgI-IM
- Protein/Peptide Name:M-CSF
- Purity:≥95%
- Molecular Weight:18.2/36.4 kDa
- Sequence:MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP
- Endotoxin Level:Low
- Formulation:10 mM Sodium phosphate, 50 mM Sodium chloride, pH 7.5
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay
Specifications
Related Information
Certificates
Search by Lot NumberLiterature reference - PubMed ID 18675819 Literature reference - PubMed ID 23329645 Literature reference - PubMed ID 24960189 Literature reference - PubMed ID 27462873 Literature reference - PubMed ID 29070690
Additional Product Details
Shenandoah_Biotechnology_Product_Catalog