Interleukin 31 (IL-31) is an immunoregulatory cytokine that is expressed by activated type 2 T helper (Th2) cells. IL-31 signals through a heterodimer receptor consisting of the IL-31 Receptor A (IL-31RA) and the oncostatin M receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.
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Shenandoah Biotechnology is a manufacturer of research grade recombinant proteins typically used as cytokines, growth factors and chemokines in cell based assays and cell culture. Each production lot is tested for QA and the expected values for each product can be viewed under the product specifications tab.
To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. Avantor will not lift restrictions for residential shipping addresses.
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:Store at –20 °C prior to opening
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:bioactive, but no test is suitable to set an Acceptance Criteria (primary cell assay, in vivo assay or cell line is not commercially available)
- Gene ID:P48061
- Reconstitution Instructions:Reconstitute with Sterile water at 0.1 mg/mL
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:N
- Protein Synonyms:CXCL12|PBSF
- UniProtKB:P48061 (2)
- Protein/Peptide Name:SDF-1alphaCXCL12
- Purity:>95%
- Molecular Weight:8 kDa
- Sequence:KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
- Endotoxin Level:Low
- Formulation:0.1% Trifluoroacetic Acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:Ambient