About this item
Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.
- High quality
- Low endotoxin
- Affordable
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Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Storage Conditions:–20 °C
- Endotoxin Content:Endotoxin LAL (EU/µg) ≤0.1
- Biological Activity:Bioactivity Assay: C₆ proliferation, ED₅₀ ≤3 µg/ml, Bioactivity ≥3.3×10² units/mg
- Gene ID:P39905
- Reconstitution Instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-Free:Y
- Protease-free:N
- Animal-Free:N
- Protein Synonyms:ATF-1
- Protein/Peptide Name:GDNF
- Purity:≥95%
- Molecular Weight:15.2/30.4 kDa
- Sequence:MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
- Endotoxin Level:Low
- Formulation:10 mM Sodium citrate, 100 mM Sodium chloride, pH 4.0
- Nuclease-free:N
- Grade:RUO
- Shipping Temperature:RT
- Tested Applications:Bioassay
Specifications
Related Information
Literature reference - PubMed ID 24473149 Literature reference - PubMed ID 25822020
Additional Product Details
Shenandoah_Biotechnology_Product_Catalog