- Antibody Type:Primary
- Antigen Name:Transcription Termination Factor RNA Polymerase 1
- Antigen Symbol:TTF1
- Clonality:Monoclonal
- Clone:2C8F3
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Mouse
- ImmunoChemistry:Yes
- Isotype:IgG3
- Reactivity:Human
- Western Blot:Yes
- Size:150 µL
- Antigen Synonyms:thyroid nuclear factor 1|thyroid transcription factor 1|TTF-1|BCH|NKX2A|TEBP|NKX2.1|TTF1|BHC|NK-2 homolog A|NK-2|homeobox protein Nkx-2.1|homeobox protein NK-2 homolog A|TITF1
- Storage Buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Peptide
- Purification:Protein A Purification
- Cat. No.:10081-256
- Supplier no.:66034-1-IG
Homeobox protein Nkx-2.1 (NKX2-1), also named Thyroid nuclear factor 1,Thyroid transcription factor 1(TTF1). It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD).
Western Blot: Hela Cells, 1:500-1:5000; IHC: Human lung cancer Tissue, 1:20-1:200
Type: Primary
Antigen: TTF1
Clonality: Monoclonal
Clone: 2C8F3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG3
Reactivity: Human