Specifications
- Antibody Type:Primary
- Antigen Name:Early growth response protein 1
- Antigen Symbol:EGR1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:150 µL
- Antigen Synonyms:nerve growth factor-induced protein A|TIS8|AT225|ZNF225|ZIF-268|NGFI-A|G0S30|KROX-24
- Storage Buffer:0.1M NaHCO3, 0.1M glycine, 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Peptide
- Purification:Antigen affinity Purification
- Cat. No.:10081-748
- Supplier no.:55117-1-AP
Specifications
About this item
Early growth response 1 (EGR1) is a member of EGR family which are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (ER) to regulate target gene expression. The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF. Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation. Egr-1 binds to the DNA sequence 5'-CGCCCCCGC-3' (Egr-site), thereby activating transcription of target genes whose products are required for mitogenesis and differentiation.
Western Blot: Mouse Brain Tissue, 1:200-1:1000; IF: HeLa Cells, 1:10-1:100; IHC: Human ovary tumor Tissue, 1:20-1:200
Type: Primary
Antigen: EGR1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse