- Antibody Type:Primary
- Antigen Name:Cullin 4B
- Antigen Symbol:CUL4B
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:150 µL
- Antigen Synonyms:CUL-4B|SFM2|MRXS15|MRXSC|MRXHF2
- Storage Buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping Temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. No.:10081-714
- Supplier no.:12916-1-AP
Cullin-RING ligases (CRLs) complexes participate in the regulation of diverse cellular processes, including cell cycle progression, transcription, signal transduction and development . Serving as the scaffold protein, cullins are crucial for the assembly of ligase complexes, which recognize and target various substrates for proteosomal degradation. Two cullin 4 (CUL4) proteins, CUL4A (87 kDa) and CUL4B(104 kDa), are two members in cullin family with 83% of identity. Mutations in human CUL4B are one of the major causes of X-linked mental retardation. Cul4b knockout mice demonstrated that CUL4B is indispensable for embryonic development in the mouse .
Western Blot: HEK-293 Cells, 1:500-1:5000; IHC: Human gliomas Tissue, 1:20-1:200; IF: HepG2 Cells, 1:10-1:100; IP: HeLa Cells, 1:500-1:5000
Type: Primary
Antigen: CUL4B
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: