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- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.005 mg
- Environmentally Preferable:
- Biological Activity:Biological activity was determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0 - 30.0 ng/mL.
- Protein Synonyms:NRN|dJ380B8.2|Neuritin
- Protein/Peptide Name:Neuritin
- Purity:>98%
- Formulation:Lyophilized
- Cat. No.:10072-600
- Supplier no.:40-507
Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.7 kDa polypeptide monomers, each containing 88 amino acid residues.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.