About this item
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant human IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.
Specifications
- Protein/Peptide Type:Recombinant
- Source:E. coli
- Species:Mouse
- Biological Activity:The ED50 was determined by the dose - dependent stimulation of the proliferation of human TF - 1 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
- Protein Synonyms:Interleukin-5|EDF|TRF|IL-5|B-cell differentiation factor I
- Protein/Peptide Name:IL5
- Purity:>98%
- Formulation:Lyophilized