Human Recombinant TGF alpha (from E. coli)
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Product Details & Documents
TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.
Documents
10072-624.pdf
Datasheet
Specifications
Specifications
- Size:0.02 mg
- Cat. No.:10072-624
- Biological Activity:The ED50 was determined by the dose - dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/mL, corresponding to a specific activity of ≥ 5 x 10<sup>6</sup> units/mg.
- Protein/Peptide Type:Recombinant
- Formulation:Lyophilized
- Purity:>98%
- Protein Synonyms:Tgf-alpha
- Protein/Peptide Name:TGF alpha
- Species:Human
- Source:E. coli
Specifications
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