Anti-APP Rabbit Polyclonal Antibody
Catalog # 10075-694
Supplier: Prosci
Specifications
- Antibody Type:Primary
- Antigen Name:amyloid beta (A4) precursor protein
- Antigen Symbol:App
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Reactivity:Human,Dog,Rat,Mouse
- Western Blot:Yes
- Size:0.1 mL
- Form:Liquid
- Gene ID:P08592
- Antigen Synonyms:APPA
- Storage Buffer:100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
- Molecular Weight:115
- Storage Temperature:Amyloid Precursor Protein antibody can be stored at –20 °C and is stable at –20 °C for at least 1 year.
- Shipping Temperature:4 °C
- Immunogen:Peptide corresponding to amino acid residues from the C-terminal region of rat APP.
- Purification:Affinity Purified
- Cat. No.:10075-694
- Supplier no.:50-179
Specifications
About this item
A large body of evidence has implicated the amyloid precursor protein (APP) in the pathogenesis of Alzheimer's disease (AD) (Kamenetz et al., 2003). The phosphorylation of APP at Thr668 is thought to play a critical role in generation of the soluble APP (beta) and beta-amyloid peptide (abeta) which are the major components of senile plaques in patient brains inflicted with AD (Liu et al., 2003; Ando et al., 2001).
- The antibody has been directly tested for reactivity in rat tissue. It is anticipated that the antibody will also work with canine, chicken, human, mouse and non-human primate tissues based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Affinity Purified
100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: App
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat, Dog