Specifications
- Antibody Type:Primary
- Antigen Name:E74-like factor 3
- Antigen Symbol:Elf3
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Reactivity:Mouse
- Western Blot:Yes
- Size:100 ul
- Form:Liquid
- Gene ID:Q3UPW2-2
- Antigen Synonyms:Elf3
- Storage Buffer:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Molecular Weight:41 kDa
- Storage Temperature:For short periods of storage (days) store at 4 °C. For longer periods of storage, store Elf3 antibody at –20 °C. As with any antibody avoid repeat freeze-thaw cycles.
- Shipping Temperature:4 °C
- Immunogen:Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse Elf3.
- Purification:Antibody is purified by peptide affinity chromatography method.
- Cat. No.:10106-560
- Supplier no.:28-574
Specifications
About this item
Elf3 is a transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. It acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter (By similarity). It also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. IT represses KRT4 promoter activity (By similarity). It may play an important role in epithelial cell differentiation and tumorigenesis and may be a critical downstream effector of the ERBB2 signaling pathway (By similarity). It may be associated with mammary gland development and involution. It plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.
Elf3 antibody can be used for detection of Elf3 by ELISA at 1:62500. Elf3 antibody can be used for detection of Elf3 by western blot at 1.0 ?g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Antibody is purified by peptide affinity chromatography method.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: Elf3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Mouse