Human Mobilized Peripheral Blood Mononuclear Cells (PBMC), Charles River Laboratories Cell Solutions

Supplier: Charles River Laboratories Cell Solutions

Supplier: Charles River Laboratories Cell Solutions

About this item

Human mobilized peripheral blood mononuclear cells (PBMC) are collected from healthy human volunteer donors under IRB approved informed consent by leukapheresis using the COBE® Spectra Apheresis System MNC collection protocol

Mononuclear cells are widely used in research and clinical applications such as in microbiology, virology, oncology, vaccine development, transplant and regenerative biology, and toxicology.

Serological and Infectious disease testing are performed with each donation. Customers should handle product as if potentially infectious following biosafety level 2 procedures.

Donors are injected with G-CSF (Neupogen® - FDA approved), which stimulates the bone marrow to produce a large number of hematopoietic and progenitor stem cells and mobilizes them into the peripheral blood stream. This mononuclear cell-rich leukapheresis product (LeukoPak) is extracted using continuous flow centrifugal technology directly into the collection bag. Mobilized mononuclear cells are purified using density gradient centrifugation techniques.

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