This antibody reacts with β-amyloid protein. This antibody stains amyloid plaques within the cortex, and amyloid deposits in blood vessels. β-amyloid deposits are also detected in Lewy body dementia, Down syndrome, amyloidosis and in Gram-Parkinson dementia complex. The presence of a large number of neuritic plaques (senile) and neurofibrillary tangles in the cerebral cortex is used as a pathological marker for a disease state and presents the major criterion for the diagnosis of Alzheimer’s disease at autopsy.

Type:
Antigen: APP
Clonality: Monoclonal
Clone: BAM-10
Conjugation:
Epitope:
Host: Mouse
Isotype:
Reactivity: 0