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Specifications
- Antibody Type:Primary
- Antigen Name:B-cell receptor-associated protein 31
- Antigen Symbol:BCAP31
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:0.1 mg
- Environmentally Preferable:
- Form:Liquid
- Gene ID:P51572
- Antigen Synonyms:BCAP31
- Storage Buffer:BAP31 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage Temperature:BAP31 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping Temperature:4 °C
- Immunogen:BAP31 antibody was raised against a 17 amino acid synthetic peptide from near the center of human BAP31. The immunogen is located within amino acids 130 - 180 of BAP31.
- Tested Applications:E, WB, IHC
- Purification:BAP31 Antibody is affinity chromatography purified via peptide column.
- Cat. No.:89415-968
- Supplier no.:3675
Specifications
About this item
BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. Bap31 may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopically, is also a potent inducer cell death.
Type: Primary
Antigen: BCAP31
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat