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Specifications
- Method / Format:Column (silica-based)
- Prep size:Mini
- Refine target molecule:Methylated DNA
- Sample type:PCR and other enzymatic reactions
- Target molecule:DNA
- Description:EpiMark Methylated DNA Enrichment Kit
- Size:25 Reactions
- Description:EpiMark Methylated DNA Enrichment Kit
- Cat. No.:101710-274
- Supplier no.:E2600S
Specifications
About this item
The EpiMark Methylated DNA Enrichment Kit enables the enrichment of double-stranded CpG methylated DNA based on CpG methylation density.
It utilizes the methyl-CpG binding domain of human MBD2a protein as a capture agent. The protein is fused to the Fc tail of human IgG1 (MBD2a-Fc), which is coupled to Protein A Magnetic Beads (MBD2a-Fc/Protein A Bead). This stable complex will selectively bind double-stranded methylated CpG containing DNA. The high binding affinity of the MBD2a-Fc coupled beads and optimized reagents increases sensitivity and accuracy. This kit contains all the individual components necessary to achieve enrichment in less than two hours using a four step process.