Human Recombinant BCMA (from HEK293 cells)

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-kappaB and JNK.

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Conjugation:
Unconjugated
Protein/Peptide Type:
Recombinant
Source:
HEK293 cells
Species:
Human
Storage Conditions:
–20 °C
Endotoxin Content:
<0.01EU/µg
Biological Activity:
Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation.
Gene ID:
Q02223
Protein Synonyms:
B Cell Maturation Protein|CD269|TNFRSF17
Protein/Peptide Name:
BCMA
Purity:
95%
Molecular Weight:
~40kDa (SDS-PAGE)
Sequence:
19756
Endotoxin Level:
Low
Concentration:
1mg/ml after reconstitution.
Formulation:
Lyophilized. Contains PBS.
Shipping Temperature:
-20 °C, Blue Ice