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Specifications
- Antibody Type:Primary
- Antigen Name:NAD(P)H Dehydrogenase, Quinone 1
- Antigen Symbol:NQO1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Reactivity:Human
- Western Blot:Yes
- Size:100 µg
- Form:Liquid
- Gene ID:Q3B792
- Antigen Synonyms:Quinone Reductase 1 (QR1)|DT-Diaphorase (DTD)|Menadione Reductase|Azoreductase|Phylloquinone Reductase|NAD(P)H Dehydrogenase (Quinine) 1 (NQO1)|Disphorase-4 (DIA4)|Dioxin-inducible 1|NAD(P)H:Quinone Oxireductase|NAD(P)H:Quinone Oxidoreductase 1
- Storage Buffer:0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Storage Temperature:Short term: +4 °C, Long Term: –20 °C
- Concentration:1mg/ml
- Shipping Temperature:-20° C
- Immunogen:Recombinant human NQO1.
- Cat. No.:102514-620
- Supplier no.:AG25A0105C100
Specifications
About this item
NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
Stable for at least 6 months after receipt when stored at -20°C.
Type:
Antigen: NQO1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human