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Specifications
- Antibody Type:Primary
- Antigen Name:Caspase 1
- Antigen Symbol:CASP1
- Clonality:Monoclonal
- Clone:Casper-1
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Isotype:IgG1
- Reactivity:Mouse
- Western Blot:Yes
- Size:100 µg
- Form:Liquid
- Gene ID:P29452
- Antigen Synonyms:Interleukin-1beta-converting Enzyme|ICE|IL-1BC|Interleukin-1beta Convertase
- Storage Buffer:In PBS containing 10% glycerol and 0.02% sodium azide.
- Storage Temperature:Short term: +4 °C, Long Term: –20 °C
- Concentration:1mg/ml
- Shipping Temperature:-20° C
- Immunogen:Recombinant mouse caspase-1.
- Cat. No.:102514-354
- Supplier no.:AG20B0042C100
Specifications
About this item
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
- Stable for at least 1 year after receipt when stored at -20°C.
Purified from concentrated hybridoma tissue culture supernatant.
Purity: >95% (SDS-PAGE)
Type:
Antigen: Caspase-1
Clonality: Monoclonal
Clone: Casper-1
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Mouse