About this item
The CD137 ligand (CD137L, 4-1BBL) is a member of the tumor necrosis factor (TNF) family. CD137L is a type II, transmembrane protein found on activated macrophages, dendritic cells and mature B cells. The interaction with its receptor 4-1BB induces recruitment of TNF receptor-associated factor 1 (TRAF1) and TRAF2 and interaction with the kinase p56lck. CD137 and CD137L have been reported to be involved in tumor rejection, apoptosis, anti-viral immunity, diabetes, in T and B cell co-stimulation and modulation of the immune response.
Type:
Antigen: CD137L
Clonality: Monoclonal
Clone: 41B436
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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Specifications
- Catalog No:
- 102514-030
- 102514-028
- Antigen Symbol:
- CD137L
- CD137L
- Antigen Name:
- Tumor Necrosis Factor (Ligand) Superfamily Member 9
- Tumor Necrosis Factor (Ligand) Superfamily Member 9
- Antigen Synonyms:
- 4-1BBL|TNFSF9
- 4-1BBL|TNFSF9
- Antibody Type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Unconjugated
- Unconjugated
- Clone:
- 41B436
- 41B436
- Reactivity:
- Human
- Human
- Host:
- Mouse
- Mouse
- Gene ID:
- P41273
- P41273
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western Blot:
- Yes
- Yes
- ELISA:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- Flow Cytometry:
- Yes
- Yes
- Immunogen:
- Recombinant human CD137L extracellular domain.
- Recombinant human CD137L extracellular domain.
- Form:
- Liquid
- Liquid
- Concentration:
- 1mg/ml
- 1mg/ml
- Storage Buffer:
- 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Storage Temperature:
- Short term: +4 °C, Long Term: –20 °C
- Short term: +4 °C, Long Term: –20 °C
- Shipping Temperature:
- -20° C
- -20° C
- Tested Applications:
- FACS
- FACS