About this item
The 19S regulatory complex consists of a ‘base’ sub-complex, composed of a hetero-hexameric ring of AAA-ATPases that not only function as the gate-opener to the 20S proteasome but also, in conjunction with two other high-molecular-mass non-ATPase subunits (Rpn2/S1 and Rpn1/S2), as a platform for protein unfolding. The ‘lid’ sub-complex of the 19S complex, composed of non-ATPase subunits is involved in the binding and deubiquitinylation of proteasome targeted ubiquitin conjugated proteins and assists in the transport of substrates through the ‘base’ and into the 20S catalytic core.
- For Western Blot
Recognizes human proteasome 19S (Rpt2/S4 subunit).
Type: Primary
Antigen: PROTEASOME 19S RPT2/S4 SUBUNIT
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human
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Specifications
- Catalog No:
- 89161-892
- 89161-894
- Antigen Symbol:
- Proteasome 19S Rpt2/S4
- Proteasome 19S Rpt2/S4
- Antigen Name:
- Proteasome 19S Rpt2/S4 Subunit
- Proteasome 19S Rpt2/S4 Subunit
- Antibody Type:
- Primary
- Primary
- Clonality:
- Polyclonal
- Polyclonal
- Reactivity:
- Human
- Human
- Host:
- Rabbit
- Rabbit
- Western Blot:
- Yes
- Yes
- Form:
- Liquid. In PBS containing 0.01% sodium azide.
- Purification:
- Partially Salt precipitation