Protein Kinase C (20-28) (Myristoylated)
89161-074
:
- Size:0.5 mg
- Form:TFA salt. lyophilized
- Enzyme Name:Protein kinase C (20-28) (myristoylated)
- Purity:≥98% (HPLC)
- Formulation:TFA salt. Lyophilized.
- Cat. No.:89161-074
- Supplier no.:P205-0500
PKC inhibitor
Pseudosubstrate sequence from PKCalpha and ß. Highly specific inhibitor, which is N-terminal myristoylated to allow membrane permeability. IC50=8 µM for TPA activation of MARCKS phosphorylation in fibroblast primary cultures, and 98% inhibition at 100 µM. Partially reverses multidrug resistance in human breast cancer cells.