MCDB 131 was originally developed by the researchers Knedler and Ham for the low-protein and serum free growth of human microvascular endothelial cells (HMVEC)

• Low endotoxin - < 0.25EU/mL
• Mycoplasma tested
• Formulated with cell culture grade WFI water
• Manufactured in a cGMP environment

Since its development, this medium has been used for this cell type and others such as liver, smooth muscle, cardiac myocytes. It is one of a group of MCDB media which were designed to provide a defined and optimally balanced nutritional environment for various mammalian cell types.