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Anti-CD3E Hamster Monoclonal Antibody [clone: 145-2C11]
Anti-CD3E Hamster Monoclonal Antibody [clone: 145-2C11]
Catalog # 89360-204
Supplier:  Genetex
Anti-CD3E Hamster Monoclonal Antibody [clone: 145-2C11]
Catalog # 89360-204
Supplier:  Genetex
Supplier Number:  GTX16181

Specifications

  • Antibody Type:
    Primary
  • Antigen Name:
    CD3 Molecule Epsilon
  • Antigen Symbol:
    CD3E
  • Clonality:
    Monoclonal
  • Clone:
    145-2C11
  • Conjugation:
    Unconjugated
  • Flow Cytometry:
    Yes
  • Host:
    Hamster
  • Isotype:
    IgG
  • Reactivity:
    Mouse
  • Size:
    250μg
  • Gene ID:
    12501
  • Antigen Synonyms:
    CD3e antigen|TCRE|epsilon subunit of T3|epsilon polypeptide TiT3 complex|T3E|FLJ18683|CD3-epsilon|T-cell surface glycoprotein CD3 epsilon chain|T-cell antigen receptor complex|T-cell surface antigen T3/Leu-4 epsilon chain
  • Storage Buffer:
    Preservative: None Constituents: PBS
  • Storage Temperature:
    Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
  • Concentration:
    0.5 mg/ml
  • Immunogen:
    Tissue / cell preparation, H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37.
  • Tested Applications:
    Fluorescence-Activated Cell Sorting
  • Purification:
    Protein G purified
  • Cat. No.:
    89360-204
  • Supplier no.:
    GTX16181

Specifications

About this item

T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.

FACS: Use 0.25?g for 10^6 cells. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Type: Primary
Antigen: CD3E
Clonality: Monoclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Hamster
Isotype: IgG
Reactivity: