- Antibody Type:Primary
- Antigen Name:A Proliferation-inducing Ligand
- Antigen Symbol:APRIL
- Clonality:Monoclonal
- Clone:Aprily-1
- Conjugation:Unconjugated
- Flow Cytometry:Yes
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Western Blot:Yes
- Size:50 μg
- Gene ID:8741
- Antigen Synonyms:APRIL|TNFSF13|TALL2|TRDL-1|CD256|UNQ383/PRO715
- Amino Acid Number:93 to 233
- Storage Buffer:Phosphate-buffered saline containing 0.02% sodium azide
- Storage Temperature:Upon Receipt - Keep as concentrated solution. Aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:1 mg/ml
- Immunogen:Recombinant human APRIL corresponding to amino acids 93-233, expressed in bacteria.
- Tested Applications:Fluorescence-Activated Cell Sorting
- Purification:Purified
- Cat. No.:89360-150
- Supplier no.:GTX16088
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for A PRoliferation-Inducing Ligand), TALL2 (for TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
For FACS: Use at a concentration of 10 ?g/ml. This antibody also works for intracellular FC staining. For WB: Use at a concentration of 1 ?g/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Type: Primary
Antigen: APRIL
Clonality: Monoclonal
Clone: Aprily-1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human