You searched for: 7-Aminoactinomycin D (7-AAD)

Supplier: Tonbo Biosciences

7-AAD (7-Aminoactinomycin D) is a nucleic acid dye that can be used to exclude nonviable cells from the analysis of flow cytometry data based on light scatter and fluorescence properties.

Supplier: Enzo Life Sciences

Fluorescent, intercalating DNA-binding agent useful for identifying apoptotic cells by flow cytometry. Capable of identifying populations representing live, apoptotic, and late apoptotic/dead cells in a quick, simple, reproducible, cost-effective fashion

Supplier: ALADDIN SCIENTIFIC

7-Aminoactinomycin D ，an analog of the antibiotic actinomycin D ，is a fluorescent DNA dye which is useful for quantifying apoptosis. 7-AAD has also been used in studies on cellular necrosis, chromosome analysis and in cell cycle studies. As a fluorescent DNA dye, 7-AAD is able to intercalate DNA via binding to the GC regions. When used in flow cytometery, 7-AAD can be used to discriminate between live cells as well as early and late apoptosis. Additionally, 7-AAD can also be combined with other staining procedures for analysis of intracellular and cell surface antigens enabling multiparametric analysis. When utilizing 7-AAD with flow cytometery, early and late apoptosis can be studied by varying the concentration of 7-AAD. During apoptosis, the cellular plasma membrane is altered progressively, which allows the cell membrane to become permeable to 7-AAD. 7-AAD staining can also be adapted to include staining with other dyes for intracellular and cell surface antigens. 7-Aminoactinomycin D is an inhibitor of DNA Polymerase and RNA PolymeraseA fluorescent DNA dye for apoptosis and flow cytomtery studies.

Supplier: AAT BIOQUEST INC

7-Amino actinomycin D (7-AAD) is a non-permeant dye that can be used to identify non-viable cells.

Supplier: Biotium

is a fluorescent dna intercalator, which upon binding to dsdna can be excited by the argon-ion laser and emits at 647 nm. 7-aad binds selectively to gc regions of dna, which makes the dye useful for chromosome banding studies.

Supplier: Anaspec Inc

Selectively binding to GC sequence.