G418 disulphate

Supplier: Enzo Life Sciences

White to off-white powder

Supplier: Corning

G418 Sulfate is recommended for use as selection agent in a concentration range of 100-800 µg/ml.

Supplier: Abcam

Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo.

Supplier: MP Biomedicals

G418 Sulfate is an aminoglycoside related to Gentamicin and is toxic to bacteria, yeast,higher plants, mammalian cells, protozoans and helminths. The resistance genes are located on transposons Tn601(903) and Tn5 and are bacterial in derivation, but they can be expressed in eukaryotic cells. By introducing these genes into cells, resistance to G418 Sulfate is conferred. G418 Sulfate is an effective selecting agent utilized in killing prokaryotic and eukaryotic cells.

Supplier: Thermo Scientific Chemicals

G418 disulfate for biochemistry

Supplier: MP Biomedicals

G418 disulfate, Molecular Formula: C20H40N4O10-2H2SO4, Molecular weight: 692.70, Format: Powder, related to Gentamicin and toxic to yeast, higher plants, mammalian cells, protozoans and helminths, polypeptide synthesis in both prokaryotic and eukaryotic cells and is useful for selection, Size: 5g

Supplier: Corning

G418 Sulphate is recommended for use as a selection agent in a concentration range of 100 to 800 µg/ml. This antibiotic blocks polypeptide synthesis by hindering protein elongation, and inhibits the selection and maintenance of eukaryotic cells stably transfected with the neomycin resistance gene. G418 is an aminoglycoside antibiotic similar in structure to gentamicin, neomycin and kanamycin. This antibiotic is effective against Gram negative and some Gram positive bacteria.

Supplier: RPI

G-418 Disulfate, also known as Geneticin, is a widely used antibiotic in the life science marketplace. It is commonly utilized as a selective agent in cell culture systems and molecular biology applications. G-418 is derived from the bacterium Micromonospora rhodorangea and belongs to the class of aminoglycoside antibiotics. It acts by inhibiting protein synthesis in cells, specifically targeting the 80S ribosome and interfering with translocation.

Supplier: Thermo Scientific Chemicals

Aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths

Supplier: Thermo Scientific Chemicals

Aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths

Supplier: Promega Corporation

An aminoglycosidic antibiotic toxic to both prokaryotic and eukaryotic cells.

Supplier: Chem-Impex International

This geneticin disulfate is plant cell culture, tested.

Supplier: G-Biosciences

Mode of Action: G-418 inhibits protein elongation by blocking polypeptide synthesis. Eukaryotic cells that are stably transfected with neomycin resistance genes can be selected and maintained using this product.

Supplier: IBI Scientific

G418 disulfate solution is routinely used as a selection antibiotic in cell culture gene selection applications

Supplier: Teknova

Geneticin is used as a selection marker in both prokaryotic and eukaryotic cell lines

Supplier: Mirus Bio

G418 antibiotic solution is used for stable cell line generation, it ensures effective positive selection for cells expressing the neomycin resistance (neo) gene. Different cell types and cell culture conditions may require different concentrations of selection antibiotic.