You searched for: Gabexate mesylate
Gabexate mesylate ≥97.0% (by total nitrogen basis)
Supplier: TCI America
Gabexate Mesylate, Purity: >97.0%(N), CAS: 56974-61-9, Molecular Formula: C16H23N3O4.CH4O3S, MW: 417.48, Synonym: 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic Acid Ethyl Ester Mesylate, Gabexate Methanesulfonate, Physical state: Solid, Form: Crystal- Powder, Size: 1G
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Gabexate mesylate ≥98% (by HPLC)
Supplier: Enzo Life Sciences
A competitive, reversible inhibitor of serine proteases tryptase (Ki=3.4nM), thrombin (Ki=500nM), uPA (Ki=1.3µM), plasmin (Ki=1.5µM), trypsin (Ki=2µM), factor Xa (Ki=2µM). At higher concentrations it inhibits kallikrein-1 (Ki=2.6mM), C1 esterase (IC50=520µM), as well as phospholipase A2 (IC50=500µM), rat iNOS (Ki=5mM) and cNOS (Ki=150µM), and swine kidney copper amine oxidase (Ki=27µM), but not chymotrypsin. Has been used in tissue culture and in vivo. In clinical use for pancreatitis.