You searched for: Radicicol

Supplier: Enzo Life Sciences

HSP90 inhibitor

Supplier: Adipogen

Radicicol is an antibiotic, protein tyrosine kinase inhibitor.

Supplier: Novus Biologicals

Radicicol inhibits src (IC50=0.27uM) and src-like kinases, leading to hypophosphorylation of retinoblastoma tumor suppressor protein. It causes morphological reversion of ras-transformed cells and leads to selective depletion of Raf kinase. It also displays anti-angiogenic activity, and binds to and inhibits Hsp 90 molecular chaperone. It binds more strongly to Hsp90 than to GRP94. It also binds to yeast HSP90, E. coli HtpG and TRAP-1.f