You searched for: AdipoRon
AdipoRon ≥98% (by HPLC)
Supplier: Enzo Life Sciences
Novel and orally active adiponectin receptor agonist for AdipoR1 and AdipoR2.
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AdipoRon ≥98%
Supplier: ALADDIN SCIENTIFIC
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
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AdipoRon ≥98% (by NMR)
Supplier: Adipogen
Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low µm concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) which boosts mitochondrial proliferation and energy metabolism. Improves diabetes, glucose and lipid metabolism and insulin sensitivity in cultured cells and in mice by AdipoR-dependent mechanisms. Rescued the shortened lifespan of db/db mice (AdipoRs KO) on high-fat diet. Reduces expression levels of genes encoding inflammatory cytokines such as TNF-alpha, IL-6 and CCL-2 in WAT of WT mice but not db/db mice.