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Glibenclamide 99%
Supplier: Thermo Scientific Chemicals
ATP-dependent potassium channel (KATP) and cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel blocker
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Glibenclamide USP
Supplier: Adipogen
Antidiabetic compound. Binds to and activates the ATP-sensitive potassium channels (KATP) inhibitory regulatory subunit sulfonylurea receptor 1 (SUR1). Causes cell membrane depolarization and opening of voltage-dependent calcium channel. Increases intracellular calcium and stimulates insulin secretion in beta cells NLRP3 inflammasome inhibitor. Broad-spectrum ATP-binding cassette (ABC) transporter inhibitor. Shown to have anti-leishmanial activity. Potential inhibitor of collagenases.
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