You searched for: Etoposide

Supplier: Enzo Life Sciences

Topoisomerase inhibitor

Supplier: MP Biomedicals

Etoposide is an important chemotherapeutic agent that is used to treat a wide spectrum of human cancers. It also belongs to the drug type plant alkaloid.

Supplier: TCI America

CAS Number: 33419-42-0
Molecular Formula: C29H32O13
Molecular Weight: 588.56
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 251

Supplier: MilliporeSigma

(VP-16). Topoisomerase II inhibitor (IC50=59.2uM). A derivative of Podophyllotoxin that has major activity against a number of tumors. Purity: >97% by HPLC. Soluble in DMSO. CAS: 33419-42-0. FW: 588.6. White solid, 25mg.

Supplier: Thermo Scientific Chemicals

Topoisomerase inhibitor and inducer of apoptosis

Supplier: Ambeed

Etoposide 98%

Supplier: G-Biosciences

Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).

Supplier: Adipogen

Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication. p53 activator. Blocks the cell cycle between the end of the S phase and the early G2 phase. Oncoprotein Mdm2 synthesis inhibitor. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcription and alternative splicing). Chemotherapeutic compound used in cancers. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation. Highly effective in mobilizing stem cells