You searched for: Simvastatin
Simvastatin ≥98% (by TLC)
Supplier: Enzo Life Sciences
HMG-CoA reductase inhibitor
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Simvastatin ≥97.0% (by HPLC)
Supplier: TCI America
CAS Number: 79902-63-9
MDL Number: MFCD00072007
Molecular Formula: C25H38O5
Molecular Weight: 418.57
Purity/Analysis Method: >97.0% (HPLC)
Form: Crystal
Color: White
Melting point (°C): 134
Specific rotation [a]20/D: 293 deg (C=1, CH3CN)
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Simvastatin ≥98% (by HPLC), Calbiochem®, Sigma-Aldrich®
Supplier: MilliporeSigma
Simvastatin, a lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation.
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(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
Supplier: Adipogen
Synthetic analog of Lovastatin. Potent competitive HMG-CoA reductase inhibitor. Anti-hypercholesterolemic agent. Cholesterol/isoprenoid biosynthesis inhibitor. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. Inhibits the isoprenylation of Ras and Rho family GTPases. Smooth muscle cell proliferation inhibitor. Anti-adhesive, immunomodulatory and anti-inflammatory compound. Proteasome modulator. Stimulates bone formation. Apoptosis inducer. Anticancer compound. Increases cellular resistance to anticancer agents such as doxorubicin and etoposides. Suppresses ICAM-1-LFA-1 interactions, which blocks virus replication and infection. Anti-hypertensive agent. Suppresses TNF-induced NF-kappaB activation.