- Antibody Type:Primary
- Antigen Name:Cytochrome P450 1A2
- Clonality:Polyclonal
- Conjugation:Alexa Fluor® 750
- Flow Cytometry:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western Blot:Yes
- Size:100 µl
- Epitope:221-320/513
- Form:Liquid
- Gene ID:1544
- Antigen Synonyms:Cytochrome P(3)450|Cytochrome P450 4|CYP1A2|P3-450|CYPIA2|Cytochrome P450-P3|P450(PA)|CP12|Cytochrome P450 1A2
- Modification:Unmodified
- Storage Buffer:Aqueous buffered solution containing 0.01 M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Molecular Weight:56 kDa
- Storage Temperature:Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Concentration:1 µg/µl
- Shipping Temperature:4 °C
- Immunogen:KLH conjugated synthetic peptide derived from human Cytochrome P450 1A2
- Tested Applications:ICC
- Purification:Purified by Protein A
- Cat. No.:76081-862
- Packaging:Vial
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Type: Primary
Antigen: Cytochrome P450 1A2
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 221-320/513
Host: Rabbit
Isotype: IgG
Reactivity: Human; Mouse; Rat
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