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Specifications
- Antibody Type:Primary
- Antigen Name:Breast carcinoma-amplified sequence 4
- Antigen Symbol:BCAS4
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Reactivity:Human,Mouse
- Western Blot:Yes
- Size:100 µg
- Epitope:N-Terminal
- Format:IgG
- Form:Liquid (sterile filtered)
- Gene ID:55653
- Antigen Synonyms:CNOL|BCAS4|Breast carcinoma-amplified sequence 4
- Concentration:1 mg/mL by UV absorbance at 280 nm
- Shipping Temperature:Dry Ice
- Immunogen:Anti-BCAS4 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 14 amino acid synthetic peptide near the N-terminus of human BCAS4.
- Purification:Anti-BCAS4 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with BCAS4 from other sources has not been determined.
- Cat. No.:10802-034
- Supplier no.:600-401-Z41
Specifications
About this item
The Breast carcinoma amplified sequence (BCAS4) gene is localized to 20q13, a region that is often amplified in breast cancers. It was isolated by the cloning of a highly overexpressed 1.3 kb transcript from the fusion of the last two exons of the BCAS3 and BCAS4 genes. This BCAS3-BCAS4 fusion transcript is only found in the MCF7 cell line, but the BCAS4 gene is also overexpressed in nine of thirteen breast cancer cell lines. The role of BCAS4 is unknown but its mRNA is highly expressed in thymus, spleen, kidney, brain, and placenta, suggesting BCAS4 plays other roles in multiple tissues.
Recommended Dilutions: ELISA: 1:10,000-1:20,000; Immunohistochemsitry: 5 µg/mL; Immunofluorescence Microscopy: 20 µg/mL; Western Blot: 1 - 2 µg/mL; contains 0.02% (w/v) Sodium Azide
Type: Primary
Antigen: BCAS4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: N-Terminal
Host: Rabbit
Isotype:
Reactivity: Human, Mouse