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240 results for Vectors, Plasmids and Libraries

You searched for: Vectors, Plasmids and Libraries

Vectors, Plasmids and Libraries

In molecular cloning, vectors are DNA molecules used to artificially deliver foreign genetic material into another cell. The four major types of vectors are plasmids, viral vectors, cosmids, and artificial chromosomes, with the most commonly used of these being plasmids. Vectors may be used for cloning, and certain vectors are specifically tailored to that exact purpose, while others may be designed specifically for transcription and protein expression. Simpler transcription vectors are used to amplify their inserted genetic material.

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VSV-Pseudovirus_SARS-COV-2 Omicron JN.1 Luciferase

VSV-Pseudovirus_SARS-COV-2 Omicron JN.1 Luciferase

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the S protein of SARS-CoV-2 (GenBank: MN908947) with multiple mutations initially identified in variant of Omicron JN.1. See mutation on our website. The S has 18-aa cytoplasmic tail truncation for optimal infection.

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pH6HTC His6HaloTag T7 Vector, 20 µg, Promega

pH6HTC His6HaloTag T7 Vector, 20 µg, Promega

Supplier: Promega Corporation

These multiple cloning site vectors are used for inducible expression of HaloTag-polyhistidine fusion proteins in E. coli and cell-free systems using the T7 RNA polymerase promoter.

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pFC27A HaloTag CMV-neo Flexi Vector, 20 µg, Promega

pFC27A HaloTag CMV-neo Flexi Vector, 20 µg, Promega

Supplier: Promega Corporation

Vectors designed for expression of C-terminal-tagged HaloTag fusion proteins in mammalian cells. Once expressed, use the HaloTag fusion protein for cell imaging of protein localization or trafficking in conjunction with the fluorescent HaloTag Ligands.

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PhiX174 RF I DNA, New England Biolabs

PhiX174 RF I DNA, New England Biolabs

Supplier: New England Biolabs (NEB)

This is the double-stranded, covalently closed, circular form of ΦX174 RF I DNA (supercoiled).

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Lambda DNA, New England Biolabs

Lambda DNA, New England Biolabs

Supplier: New England Biolabs (NEB)

Duplex DNA is isolated from bacteriophage lambda (cI857ind 1 Sam 7)

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pFN10A (ACT) Flexi Vector, 20 µg, Promega

pFN10A (ACT) Flexi Vector, 20 µg, Promega

Supplier: Promega Corporation

The CheckMate/Flexi Vector Mammalian Two-Hybrid System provides a means to study suspected interactions between two proteins or domains and can also be used to generate stable cell lines for cell-based assays.

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pRL-SV40 Vector, 20 µg, Promega

pRL-SV40 Vector, 20 µg, Promega

Supplier: Promega Corporation

The pRL Vectors are wildtype Renilla luciferase control reporter vectors, which provide constitutive expression of Renilla luciferase and can be used in combination with a firefly luciferase vector to cotransfect mammalian cells.

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pFN2K (GST) Flexi Vector, 20 µg, Promega

pFN2K (GST) Flexi Vector, 20 µg, Promega

Supplier: Promega Corporation

These vectors are used for inducible expression of N-terminal GST-tagged fusion proteins in E. coli and cell-free systems using the T7 RNA polymerase promoter.

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psiCHECK-2 Vector, 20 µg, Promega

psiCHECK-2 Vector, 20 µg, Promega

Supplier: Promega Corporation

psiCHECK-1 and psiCHECK-2 Vectors enable monitoring of changes in expression of a target gene fused to a reporter gene. They are used for optimizing RNA interference assays.

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pGL4.14[luc2/Hygro] Vector, 20 µg, Promega

pGL4.14[luc2/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

The pGL4.14[luc2/Hygro], pGL4.15[luc2P/Hygro] and pGL4.16[luc2CP/Hygro] Vectors have different luc2 genes that code for luciferase proteins with different stabilities. Each vector offers hygromycin for stable selection.

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pBIND-ER(alpha) Vector, 20 µg, Promega

pBIND-ER(alpha) Vector, 20 µg, Promega

Supplier: Promega Corporation

NR ligand binding domain fused to yeast GAL4 TF DBD in the FN26A (BIND) Flexi Vector or use pBIND-Er∝ and pBIND-GR Vectors. Fusion protein NR activates luc2P reporter controlled by 9X GAL4 UAS in pGL4.35. Use pGL4.36 MMTV LTR for androgen or GC responses.

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pGL4.54[luc2/TK] Vector, 20 µg, Promega

pGL4.54[luc2/TK] Vector, 20 µg, Promega

Supplier: Promega Corporation

pGL4.13[luc2/SV40] ,pGL4.53[luc2/PGK] and pGL4.54[luc2/TK] Vectors are used as controls in dual-luciferase assays where Renilla or NanoLuc luciferase is the experimental reporter. Select the appropriate promoter or test all 3 in your experimental system.

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pGL4.22[luc2CP/Puro] Vector, 20 µg, Promega

pGL4.22[luc2CP/Puro] Vector, 20 µg, Promega

Supplier: Promega Corporation

The pGL4.20[luc2/Puro], pGL4.21[luc2P/Puro] and pGL4.22[luc2CP/Puro] Vectors are optimized for expression in mammalian cells. The luc2 genes code for luciferase proteins with different stabilities, and each vector offers puromycin for stable selection.

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pNLF1-secN [CMV/Hygro] Vector, 20 µg, Promega

pNLF1-secN [CMV/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

The three pNLF1 Vectors create N- or C-terminal fusions of NanoLuc luciferase and your protein of interest using a multiple cloning site (MCS). Insert your protein on the N or C terminus of NanoLuc luciferase or the N terminus of secreted NanoLuc enzyme.

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VSV-Pseudovirus_Sudan Ebola Luciferase, ReVacc Scientific

VSV-Pseudovirus_Sudan Ebola Luciferase, ReVacc Scientific

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry GP protein of Sudan ebolavirus strain (GenBank: KT878488.1).

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NanoBRET Positive Control, 2 × 20 µg, Promega

NanoBRET Positive Control, 2 × 20 µg, Promega

Supplier: Promega Corporation

The NanoBRET Positive Control Vector encodes a NanoLuc-HaloTag fusion protein that tethers together the NanoLuc donor and HaloTag acceptor proteins to ensure efficient energy transfer.

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pNLCoI2[luc2-P2A-NlucP/minP/Hygro] Vector, 20 µg, Promega

pNLCoI2[luc2-P2A-NlucP/minP/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

The pNLCoI Vectors comprise a second-generation coincidence reporter vector system that allow expression of both firefly luciferase (luc2) and NanoLuc Luciferase fused to a PEST destabilization domain (NlucP) from the same mRNA transcript.

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PH.D.™-12 Phage Display Peptide Library, New England Biolabs

PH.D.™-12 Phage Display Peptide Library, New England Biolabs

Supplier: New England Biolabs (NEB)

The Ph.D.™-12 Phage Display Peptide Library is based on a combinatorial library of random dodecapeptides fused to a minor coat protein (pIII) of M13 phage

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VSV-Pseudovirus_SARS-CoV-2 Omicron BA.2.12.1 Strain Spike with Luciferase Reporter

VSV-Pseudovirus_SARS-CoV-2 Omicron BA.2.12.1 Strain Spike with Luciferase Reporter

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant vesicular stomatitis virus (rVSV) to carry the S protein of SARS-CoV-2 (GenBank: MN908947) with multiple mutations initially identified in variant of Omicron BA.2.12.1. The S has 18-aa cytoplasmic tail truncation for optimal infection.

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VSV-Pseudovirus_SARS-CoV-2 D614G Luciferase, ReVacc Scientific

VSV-Pseudovirus_SARS-CoV-2 D614G Luciferase, ReVacc Scientific

Supplier: ReVacc Scientific

This pseudotyped virus uses recombinant Vesicular Stomatitis Virus (rVSV) to carry the S protein mutated from D (Asp) to G (Gly) at site of 614 of SARS-CoV-2 (GenBank: MN908947), with 18-aa cytoplasmic tail truncation for optimal infection.

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Lenti-Pseudovirus_SARS-CoV Luciferase, ReVacc Scientific

Lenti-Pseudovirus_SARS-CoV Luciferase, ReVacc Scientific

Supplier: ReVacc Scientific

This pseudotyped virus uses Lentiviral vectors to package full-length S protein of SARS-CoV (2003 strain) (GenBank: DQ412594.1).

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pUC19 Vector, New England Biolabs

pUC19 Vector, New England Biolabs

Supplier: New England Biolabs (NEB)

pUC19 is a commonly used plasmid cloning vector in E.coli

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M13mp18 RF I DNA, New England Biolabs

M13mp18 RF I DNA, New England Biolabs

Supplier: New England Biolabs (NEB)

M13mp18 is the double-stranded, covalently closed, circular form of DNA derived from bacteriophage M13.

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pCLIPf Vector, New England Biolabs

pCLIPf Vector, New England Biolabs

Supplier: New England Biolabs (NEB)

pCLIPf Vector is a mammalian expression plasmid intended for the cloning and stable or transient expression of CLIP-tag® protein fusions in mammalian cells

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pSNAP-TAG® (T7)-2 Vector, New England Biolabs

pSNAP-TAG® (T7)-2 Vector, New England Biolabs

Supplier: New England Biolabs (NEB)

pSNAP-tag (T7)-2 Vector is an Escherichia coli expression plasmid encoding the SNAP-tag protein

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pGloSensor-20F cAMP Plasmid, 20 µg, Promega

pGloSensor-20F cAMP Plasmid, 20 µg, Promega

Supplier: Promega Corporation

The GloSensor cAMP Assay is based on a genetically modified form of firefly luciferase into which a cAMP-binding protein moiety has been inserted. This live-cell assay excels at kinetic and modulation studies of signaling through cAMP.

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pHTC HaloTag CMV-neo Vector, 20 µg, Promega

pHTC HaloTag CMV-neo Vector, 20 µg, Promega

Supplier: Promega Corporation

Vectors designed for expression of N-terminal-tagged HaloTag fusion proteins in mammalian cells. Once expressed, use the HaloTag fusion protein for cell imaging of protein localization or trafficking in conjunction with the fluorescent HaloTag Ligands.

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pF9A CMV hRluc-neo Flexi Vector, 20 µg, Promega

pF9A CMV hRluc-neo Flexi Vector, 20 µg, Promega

Supplier: Promega Corporation

The Flexi Vector System is a simple, yet powerful, directional cloning method for protein-coding sequences.

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pSP72 Vector, 20 µg, Promega

pSP72 Vector, 20 µg, Promega

Supplier: Promega Corporation

Used as standard cloning vector or for transcription of RNA in vitro.

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pGL4.30[luc2P/NFAT-RE/Hygro] Vector, 20 µg, Promega

pGL4.30[luc2P/NFAT-RE/Hygro] Vector, 20 µg, Promega

Supplier: Promega Corporation

pGL4.44[luc2P/AP1 RE/Hygro], pGL4.49[luc2P/TCF-LEF RE/Hygro], pGL4.29[luc2P/CRE/Hygro], pGL4.30[luc2P/NFAT-RE/Hygro], pGL4.32[luc2P/NF-κB-RE/Hygro], pGL4.33[luc2P/SRE/Hygro] and pGL4.34[luc2P/SRF-RE/Hygro] Vectors can explore various signaling pathways.

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