58678 Wyniki dla: „Cayman Chemical”

Supplier: Cayman Chemical

Rivastigmine is an irreversible inhibitor of acetylcholinesterase (IC₅₀=4,15 µm) and butyrylcholinesterase (IC₅₀=37 nM).

Supplier: Cayman Chemical

Imipenem is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0,5 - 2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.

Supplier: Cayman Chemical

Paroxetine is a phenylpiperidine derivative that potently and selectively inhibits the reuptake of serotonin, blocking the human serotonin transporter with a Ki value of 0,72 nM.

Supplier: Cayman Chemical

Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM).

Supplier: Cayman Chemical

Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (K_is = 0.8 nM).

Supplier: Cayman Chemical

Arachidonic acid (Item No. 90010) is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes.

Supplier: Cayman Chemical

A complete system for quantifying complex I inhibition.

Supplier: Cayman Chemical

For direct quantification of cAMP from a variety of biological samples.

Supplier: Cayman Chemical

Salicin is an alcoholic β-glucoside derived from willow bark that produces anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin. It acts as a non-selective COX inhibitor, exhibiting IC50 values >100 µM for COX-1 and COX-2.

Supplier: Cayman Chemical

2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol (2-AG), is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases. 2-OG is an agonist of GPR119 (EC₅₀ = 2.5 µM), stimulating the release of glucagon-like peptide-1 from intestinal L-cells.

Supplier: Cayman Chemical

NF-κB is a ubiquitously expressed transcription factor composed of varied combinations of five subunits: p65/RelA, RelB, c-Rel, p105/p50, and p100/p52. The NF-κB p50 subunit is a truncated version of p105 that lacks ankyrin repeat domains. The p105 subunit can be phosphorylated by GSK3β, which prevents p105 processing and degradation in resting cells. In TNF-α-stimulated cells, GSK3β phosphorylation induces processing of p105 into p50, which forms a heterodimer with p65 and is translocated to the nucleus to initiate the transcription of a variety of genes involved in innate and adaptive immunity.

Supplier: Cayman Chemical

11-Oxoetiocholanolone is a metabolite of cortisol that is found in the feces of ungulates and other animals. Stress-induced glucocorticoids (cortisol, corticosterone) traditionally have been measured through blood sampling, but the collection process is known to cause stress in animals, interfering with experimental results.

Supplier: Cayman Chemical

ZZW-115 trihydrochloride ≥95%

Supplier: Cayman Chemical

3',4'-Dihydroxyphenylacetone (Item No. 19522) is an analytical reference standard. It is a minor metabolite of 3,4-MDEA (Item Nos. 14085 | 15689), MDMA, and α-methyldopa produced by oxidative deamination.1,2,3 This product is intended for forensic and research applications.

Supplier: Cayman Chemical

Virginiamycin complex is a complex containing two streptogramin antibiotics, virginiamycin M1 (75%) and virginiamycin S1 (25%), produced by S. virginiae.

Supplier: Cayman Chemical

Anti-PAF Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Anti-mPGES-2 Rabbit Polyclonal Antibody (KLH (Keyhole Limpet Hemocyanin))

Supplier: Cayman Chemical

Anti-PINK1 Rabbit Polyclonal Antibody

Supplier: Cayman Chemical

Q-VD-OPH is a broad-spectrum caspase inhibitor, blocking caspases-3, -7, -8, -9, -10, and -12 and inhibiting apoptosis when used at 10 µm. It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK and Boc-D-FMK.

Supplier: Cayman Chemical

For the measurement of NET-derived neutrophil elastase.

Supplier: Cayman Chemical

HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC₅₀= 6 nM) that poorly blocks other HDAC enzymes.

Supplier: Cayman Chemical

HA-100 is an isoquinoline compound with an added piperazinylsulfonyl group that acts as an inhibitor of protein kinases (PKs), including PKA, PKC, and PKG (IC₅₀s = 8, 12 and 4 µM, respectively). It less effectively blocks the activity of myosin light chain kinase (IC₅₀ = 240 µM).

Supplier: Cayman Chemical

7-Ethoxyresorufin (7-ER) is a fluorometric substrate for and competitive inhibitor of cytochrome P450 1A1 (K_m ranges from 0,11-0,23 µM; IC₅₀ = 0,1 µM)

Supplier: Cayman Chemical

3'3'-cGAMP (sodium salt) ≥98%

Supplier: Cayman Chemical

CCVJ is a fluorescent molecular rotor characterised by low background fluorescence, low fluorescence anisotropy, and good water solubility. Fluorescent molecular rotors are molecules whose fluorescence is inversely proportional to its intramolecular rotation.

Supplier: Cayman Chemical

Biotin hydrazide is a biotinyl derivative used to label surface functional groups, antibodies, lectins, sugars, nucleic acids, or molecules with free carboxylic or keto groups.

Supplier: Cayman Chemical

A synthetic peptide corresponding to the nuclear localisation sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

Supplier: Cayman Chemical

HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize.

Supplier: Cayman Chemical

Aloe-emodin is a hydroxyanthraquinone found in aloe vera leaves that has potent laxative action by inducing chloride secretion in colonic mucosa and releasing acetylcholine, which stimulates contraction of intestinal smooth muscle.

Supplier: Cayman Chemical

The vial contains 700 μg of 2,6-dichlorophenolindophenol (DCPIP) assay reagent dissolved in UltraPure water. Thaw the reagent prior to use in the MitoCheck® Complex II Activity Assay Kit.