19130 Results for: "pdk&pageNo=11&view=easy"

Supplier: Cayman Chemical

11β-13,14-dihydro-15-keto Prostaglandin F2α-d4 1 * 50 µG

Supplier: Thermo Fisher Scientific

TIP CONE MODULE 1-CH.40-200UL 1 * 1 items

Supplier: IKA

The RCT basic magnetic stirrer provides reliability, an exceptionally long product lifetime and the highest safety standards. RCT basic is suitable for stirring tasks up to 20 L (H₂O) and reaches temperatures up to 310 °C. With the connection option for an external temperature sensor (PT1000.60), the temperature can be measured and controlled directly in the reaction medium. Thanks to insulation of the aluminium heating plate, maintenance-free EC motor and electronic switching power supply, RCT basic features excellent energy efficiency as well as reduced self-heating of the heating plate during stirring operation, contributing to a more sustainable laboratory.

Supplier: NEUBERT VOLUME GLASSWAERE

CRUCIBLE LOW FORM 11ML NO LID QUARTZ 1 * 1 items

Supplier: Cayman Chemical

2,3-DINOR-11Β-PROSTAGLANDIN F2Α-D9 1 * 50 µG

Supplier: VWR Collection

Stainless steel circulating baths with choice of Advanced Programmable or Advanced Digital temperature controller. Both are easy to navigate with large, intuitive displays and multiple communication options, including USB-A and B, RS232/485, Ethernet and external temperature probe. The reservoir drain can be accessed by removing the front panel. All models feature user-adjustable, high temperature safety cut-off points, as well as over-temperature protection. The surface is cool to the touch, even when operating at high temperatures.

Supplier: Greisinger

CASE GKK252 PLASTIC 235X185X48MM 1 * 1 items

Supplier: Bioss

Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.

Supplier: Bioss

Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.

Supplier: MACHEREY-NAGEL

Filter paper folded MN 611 1/4 11cm diameter, pack of 100. 1 * 100 items

Supplier: Bioss

Tumor suppressor serine/threonine-protein kinase that controls the activity of AMP-activated protein kinase (AMPK) family members, thereby playing a role in various processes such as cell metabolism, cell polarity, apoptosis and DNA damage response. Acts by phosphorylating the T-loop of AMPK family proteins, thus promoting their activity: phosphorylates PRKAA1, PRKAA2, BRSK1, BRSK2, MARK1, MARK2, MARK3, MARK4, NUAK1, NUAK2, SIK1, SIK2, SIK3 and SNRK but not MELK. Also phosphorylates non-AMPK family proteins such as STRADA, PTEN and possibly p53/TP53. Acts as a key upstream regulator of AMPK by mediating phosphorylation and activation of AMPK catalytic subunits PRKAA1 and PRKAA2 and thereby regulates processes including: inhibition of signaling pathways that promote cell growth and proliferation when energy levels are low, glucose homeostasis in liver, activation of autophagy when cells undergo nutrient deprivation, and B-cell differentiation in the germinal center in response to DNA damage. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton. Required for cortical neuron polarization by mediating phosphorylation and activation of BRSK1 and BRSK2, leading to axon initiation and specification. Involved in DNA damage response: interacts with p53/TP53 and recruited to the CDKN1A/WAF1 promoter to participate in transcription activation. Able to phosphorylate p53/TP53; the relevance of such result in vivo is however unclear and phosphorylation may be indirect and mediated by downstream STK11/LKB1 kinase NUAK1. Also acts as a mediator of p53/TP53-dependent apoptosis via interaction with p53/TP53: translocates to the mitochondrion during apoptosis and regulates p53/TP53-dependent apoptosis pathways. In vein endothelial cells, inhibits PI3K/Akt signaling activity and thus induces apoptosis in response to the oxidant peroxynitrite (in vitro). Regulates UV radiation-induced DNA damage response mediated by CDKN1A.

Supplier: Cayman Chemical

11β-13,14-dihydro-15-keto Prostaglandin F2α-d9 1 * 50 µG

Supplier: LACONT UMWELTTECHNIK

Pojistka tavná 1 * 1 KS

Supplier: BUCHI

Hose waste drain, EPDM L=1,8m 1 * 1 items

Supplier: LGC Standards PROMOCHEM

Aqueous Ethanol Standard (0.5 g/l) 10 x 1.2 mL 1 * 10 items

Supplier: UVEX

Leather Glove HexArmor Chrome Series 4080 size XXL 1 * 1 PAIR

Supplier: IKA

Laboratory stirrers designed for simple stirring tasks for quantities up to 15 or 25 L (EUROSTAR 20 digital and EUROSTAR 40 digital), or for intensive stirring tasks for quantities up to 20 L (EUROSTAR 20 high speed digital). Units automatically adjust the speed through microprocessor controlled technology within the speed range of 0/30 to 2000 min⁻¹ (or 0/150 to 6000 for the high speed model). Safety circuits ensure automatic cut off in anti-stall or overload conditions. The actual shaft speed and preset speed are constantly monitored and variations are adjusted automatically. This guarantees a constant speed even with changes in sample viscosities.

Supplier: Portwest

Versatile and comfortable protection against all weather conditions. The detachable fur lining and collar, in combination with the zip-out sleeves, prove this is a superbly adaptable garment. Numerous zipped outer and interior pockets afford excellent personal security. Two-way zip for quick and easy access.

Supplier: MACHEREY-NAGEL

Filter paper circles MN 605 11cm diameter, pack of 100. 1 * 100 items

Supplier: BIOTIX

This new generation of tips form an excellent seal on both single- and multi-channel pipettes guaranteeing total recovery of the sample whilst protecting the technician against the risks of repetitive strain injury. The tips are manufactured with proprietary technologies for increased pipetting accuracy and precision.

Supplier: LAUDA

O-RING ID. 11.0X2.0MM FPM 80SH 1 * 1 items

Supplier: TRESTON

Foot rest, bar 550x350 height adjustable 1 * 1 items

Supplier: Agilent

5Cg Hp-Ffap 30M 0.25Mm 0.25Um 1 * 1 items

Supplier: HUBER

connecting cable Combox 1 * 1 items

Supplier: MACHEREY-NAGEL

Filter paper folded MN 704 1/4 11cm diameter, pack of 100. 1 * 100 items

Supplier: LACONT UMWELTTECHNIK

Planžeta aretovací 1 * 1 KS

Supplier: HUBER

connecting cable bracket board RS232 1 * 1 items

Supplier: MACHEREY-NAGEL

Filter paper circles MN 612 11cm diameter, pack of 100. 1 * 100 items

Supplier: MACHEREY-NAGEL

Filter paper folded MN 651 1/4 11cm diameter, pack of 100. 1 * 100 items

Supplier: MACHEREY-NAGEL

Filter paper circles MN 704 11cm diameter, pack of 100. 1 * 100 items